
Kliniska studier vid Tema Cancer
–Studier öppna för inklusion inom PO Bäckencancer–
Här visas de studier som är öppna för patientinklusion inom den medicinska enheten (ME). Studierna är uppdelade på de olika patientflödena. Vidare visas ansvarig prövare, forskningssjuksköterska och planerad och aktuell inklusion inom temat (visas ej utanför Karolinska). Listan uppdateras minst en gång i veckan. -Längst ner finns en förklaring till de olika kolumnerna.
Kolorektal cancer
Nr | Namn | Fas |
Startdatum | Ansvarig prövare |
17/314 |
Watch and wait. Watch and wait-Icke operativ behandling vid strål- och cellgiftsbehandling. |
Ej tillämpbar |
2016-08-08 |
Anna Martling |
20/053 |
PRORECT. Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT):A Prospective Randomized Swedish Phase II Trial |
2 |
2021-03-08 |
Alexander Valdman |
20/073 |
CIM-HIPEC. The native immune system and the development of carcinomatosis among patients with colorectal cance |
Ej tillämpbar |
2020-01-10 |
Caroline Nordenvall |
20/074 |
CIM-IBD. Single-cell analysis of intestinal lymphocytes reveals targets for treatment of inflammatory bowel disease |
Ej tillämpbar |
2019-06-13 |
Caroline Nordenvall |
20/075 |
CITCCA pilot. CIrculating Tumour DNA in Colorectal CAncer, pilotstudie |
Ej tillämpbar |
2020-10-22 |
Anna Martling |
20/076 |
CRUISE. Restorative treatment with ileorectal anastomosis or ileal pouch anal anastomosis in patients with ulcerative colitis |
Ej tillämpbar |
2017-03-01 |
Caroline Nordenvall |
21/046 |
EFFIPEC. EFFIPEC – Efficacy of Hyperthermic Intraperitoneal ChemotherapySingle-arm Phase I study, followed by an open-label, randomized, controlled registry-based phase III trial |
1 |
2022-10-30 |
Gabriella Palmer |
22/019 |
PelvEx II. Induction chemotherapy followed by chemoradiotherapy versus chemoradiotherapy alone as neoadjuvant treatment for locally recurrent rectal cancer |
3 |
2022-08-17 |
Henrik Iversen |
24/082 |
HILOS. HIPEC and LOng of Stay - Patienters upplevelse och erfarenheter av högspecialiserad buk- och bäckencancerkirurgi |
Ej tillämpbar |
2024-11-22 |
Tina Gustavell |
24/088 |
SELSA. Selective defunstionen stoma approach in low anterior resection for rectal cancer(SELSA): a prospective study and a nested randomised clinical trial |
Ej tillämpbar |
2024-10-31 |
Naseer Baloch |
Gynekologisk cancer
Nr | Namn | Fas |
Startdatum | Ansvarig prövare |
18/080 |
RACC. The RACC trial -Robot Assisted Approach to Cervical Cancer |
3 |
2019-05-27 |
Henrik Falconer |
19/044 |
SCAN-Mi-studien-cervix. Mikrobiomets associerade biomarkörers betydelse för utveckling och prognos av livmoderhals- och huvudhals-cancer. |
Ej tillämpbar |
2021-05-01 |
Henrik Falconer |
19/058 |
TITANIUM. GestaTIonal TrophoblAstic NeoplasIa assessMent |
Ej tillämpbar |
2022-01-01 |
Ulrika Joneborg |
21/107 |
GeMore-studien. Genetisk och molekylär kartläggning samt riktad behandling inom gynekologisk cancer |
Ej tillämpbar |
2021-01-02 |
Josefin Fernebro |
21/108 |
ISGA-studien (pre-GAT01). studier av immunsystemet hos patienter med gyncancer |
Ej tillämpbar |
2021-10-21 |
Emelie Wallin |
22/077 |
ct-DNA-studien på cervixcancer. Analys av cell-fritt tumör-DNA i blod. |
Ej tillämpbar |
2022-01-01 |
Kristina Hellman |
23/004 |
PARP-PET. [11C]AZ14193391 - PET as a selection tool for treatment with PARP inhibitors in patients with metastatic solid tumors |
Ej tillämpbar |
2025-01-30 |
Rimma Axelsson/ onk: Josefin Fernebro |
23/028 |
FOLERO. Frailty, quality Of Life and Early Reversal of temporary defunctioning Stoma in Ovarian Cancer |
Ej tillämpbar |
2024-02-29 |
Sahar Salehi, Daniel Hunde |
23/043 |
MK-2870-005/ENGOT-en23. A Phase 3, Randomized, Active-controlled, Open-label, Multicenter Study to Compare the Efficacy and Safety of MK-2870 Monotherapy Versus Treatment of Physician’s Choice in Participants with Endometrial Cancer Who Have Received Prior Platinum-based Chemotherapy and Immunotherapy |
3 |
2024-04-23 |
Magnus Frödin-Bolling |
24/039 |
MK2870-020-Cervix. A Phase 3 Randomized, Active-controlled, Open-label, Multicenter Study to Compare the Efficacy and Safety of MK-2870 Monotherapy Versus Treatment of Physician’s Choice as Second-line or Third-line Treatment for Participants with Recurrent or Metastatic Cervical Cancer (MK-2870-020/GOG-3101/ENGOT-Cx20) |
3 |
2024-10-30 |
Kristina Hellman |
Prostatacancer
Nr | Namn | Fas |
Startdatum | Ansvarig prövare |
14/37 |
SPCG-15. Primary radical prostatectomy versus primary radiotherapy for locally advanced prostate cancer: an open randomized clinical trial |
3 |
2014-10-01 |
Mats Olsson |
18/034 |
PSMA recidiv-studien. En randomiserad jämförelse mellan konventionell "Salvage" strålbehandling och individualiserad PSMA-pet styrd behandling hos patienter med biokemiskt återfall (PSA) efter prostatacancer operation |
2 |
2018-10-30 |
Stefan Carlsson |
18/066 |
ProBio . ProBio: An outcome-adaptive and randomized multi-arm biomarker driven study in patients with metastatic castrate resistant prostate cancer mCRPC) |
2 |
2019-05-27 |
Anders Ullén |
21/023 |
MK3475-365. Phase Ib/II Trial of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (mCRPC) |
1-2 |
2022-04-01 |
Enrique Castellanos |
21/048 |
PRIS. Prostate Cancer IRE Study (PRIS) – A randomized controlled trial comparing focal to radical treatment in localized prostate cancer |
3 |
2022-09-07 |
Anna Lantz |
22/038 |
METRO. Metastasis directed Stereotactic Body Radiotherapy (SBRT) for Oligo metastatic Hormone sensitive Prostate Cancer |
3 |
2023-10-19 |
Mattias Hedman |
23/068 |
CAAA617A12402. Phase IV, Post-Authorization Safety Study to Investigate the Long-Term Safety of lutetium (177Lu) vipivotide tetraxetan in Adult Participants with Prostate Cancer |
4 |
2024-01-30 |
Enrique Castellanos |
23/069 |
OMAHA-003. A Phase 3 Randomized, Open-label Study of MK-5684 versus Alternative Abiraterone Acetate or Enzalutamide in Participants with metastatic Castration Resistant Prostate Cancer (mCRPC) Previously Treated with Next-generation Hormonal Agent (NHA) and Taxane-based Chemotherapy |
3 |
2024-05-10 |
Enrique Castellanos |
23/072 |
OMAHA-004. A Phase 3, Randomized, Open-label Study of MK-5684 Versus Alternative Abiraterone Acetate or Enzalutamide in Participants with Metastatic Castration-resistant Prostate Cancer (mCRPC) That Progressed On or After Prior Treatment with One Nextgeneration Hormonal Agent (NHA) |
3 |
2024-06-01 |
Anna Kristiansen |
24/016 |
IPA. Incontinence Post robot assisted radical prostatectomy, Anatomical and functional causes |
Ej tillämpbar |
2024-11-14 |
Stefan Carlsson |
Blåscancer
Nr | Namn | Fas |
Startdatum | Ansvarig prövare |
21/041 |
BioBladder. Biomarker profiling to predict response and survival in patients receiving systemic therapy for advanced urothelial cancer |
Ej tillämpbar |
2022-03-10 |
Anders Ullén |
21/067 |
RWD Avelumab. A Swedish nationwide real-world data study of maintenanceavelumab in patients with advanced urothelial cancer withoutprogression following first-line platinum-based chemotherapy |
4 |
2022-08-15 |
Faith Jawdat |
23/056 |
SGNDV-001/KN-D74. An Open-label, Randomized, Controlled Phase 3 Study of Disitamab Vedotin in Combination with Pembrolizumab Versus Chemotherapy in Subjects with Previously Untreated Locally Advanced or Metastatic Urothelial Carcinoma that Expresses HER2 |
3 |
2024-12-10 |
Anders Ullén |
23/057 |
V940-005-00-Blåsa. A Phase 2, Randomized, Double-Blind, Placebo- and Active-Comparator-Controlled Clinical Study of Adjuvant V940 (mRNA-4157) Plus Pembrolizumab Versus Adjuvant Placebo Plus Pembrolizumab in Participants with High-Risk Muscle-Invasive Urothelial Carcinoma Post-Radical Resection |
2 |
2024-06-01 |
Anders Ullen |
Njur- och testikelcancer
Nr | Namn | Fas |
Startdatum | Ansvarig prövare |
19/002 |
TINCA II - njurcancer. Det immunologiska landskapet i njurcancer |
Ej tillämpbar |
2021-09-01 |
Ulrika Harmenberg |
Urologiska sjukdomar
Tyvärr är inga studier aktuella just nu. |
Nr: Forskningsrådets nummer.
Namn: Studiens kortnamn följt av protokollets hela titel.
Fas: Kan vara Fas 1, 2, 3 eller Pilot, kombinationer av dessa, eller Ej tillämpligt.
Startdatum: Vanligen datum för startmöte eller
liknande.
Ansvarig prövare: Den läkare som är ansvarig
för studien inom Tema Cancer.
Ansvarig forskn.sköt: Den forskningssjuksköterska
som är ansvarig.
CKC, Tema Cancer, Karolinska universitetssjukhuset 11.05.2025